Why is Armodafinil a Controlled Substance?

Why is Armodafinil a Controlled Substance?
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Usage Restrictions

  • Armodafinil Waklert 150 tablets are approved in obstructive sleep apnea for the treatment of excessive drowsiness, but not the underlying blockage. Maximal efforts should be made to treat with continuous positive airway pressure (CPAP) for an acceptable amount of time before starting Armodafinil tablets for excessive drowsiness if CPAP is the therapy of choice for the patient.

How Much Armodafinil to Take and How to Take It for Narcolepsy and OSA

Medicine for Night Shift Disorder (SWD) 

  • Patients with SWD should take 150 mg of Armodafinil tablets orally once a day, preferably within an hour of the start of their work shift.

Patients with Severe Hepatic Impairment May Need a Lower Dose

  • Artvigil tablets should be given at a lower dose to individuals with significant hepatic impairment [see Use in Special Populations and Clinical Pharmacology.

Treatment of the Elderly

  • The elderly may benefit from lower dosages and strict supervision.

Different Dosage Strengths and Forms

  • The 50mg Armodafinil pills come as a spherical, uncoated, white to off-white pill with the letters “K” and “58” debossed on one side.
  • Armodafinil 150 mg tablets are round, uncoated, and white to off-white in colour; one side is debossed with “K” and the other with “59.”
  • The 200 mg Armodafinil pills come as a rounded, off-white, rectangular, uncoated tablet with a ’10’ and an ‘N’ debossed on one side.
  • The 250mg Tablets are uncoated, oval, and white to off-white in colour, with the letters “K” and “60” debossed on one side.


  • Patients with a known hypersensitivity to modafinil, Armodafinil, or any of the inactive chemicals in the tablets should not take them.

Cautionary Notes and Safety Instructions

  • Severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis
  • Armodafinil and modafinil have both been linked to severe rashes in certain users, some of which were so severe that they required hospitalisation and treatment termination (the racemic mixture of S- and R-enantiomers).
  • No studies have been done in paediatric patients, and Armodafinil is not licenced for use in children and adolescents for any purpose.
  • One case of possible Stevens-Johnson syndrome (SJS) and one case of apparent multi-organ hypersensitivity reaction/ Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) were reported in paediatric patients (age 17 years) taking modafinil in clinical trials and were serious enough to cause discontinuation of treatment [see Warnings and Precautions (5.2)]. There was a correlation between fever and other irregularities in many of the instances (e.g., vomiting, leukopenia). The typical duration of exposure to a rash before giving up was 13 days. Among the 380 young patients who got a placebo, there were no similar occurrences.
  • In the postmarketing scenario, modafinil and Armodafinil have been associated with reports of skin and mouth sores, blistering, and ulceration. Some people who have had severe skin responses claim that their symptoms returned after being rechallenged.
  • Modafinil and Armodafinil have been on the market for quite some time, and in that time there have been a few reports of severe or fatal rashes in both adults and children. These rashes include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis.
  • Modafinil and Smart Pill Armodafinil have both been linked to skin reactions, however, the likelihood of a rash occurring or the severity of an existing one cannot be predicted based on any known criteria, including the length of treatment. Serious rashes were observed anywhere from 1 day to 2 months after starting therapy, while there have been rare reports of such responses appearing much later in treatment.
  • Armodafinil may cause major skin reactions, although it is also possible to have less severe reactions. So, if you get a rash, sores, blisters, or ulcers on your skin or mouth, it’s best to stop taking Armodafinil immediately and see your doctor to rule out any medication interactions. Treatment interruption may not prevent a potentially fatal, debilitating, or disfiguring rash.

The presence of eosinophils is common. The symptoms of this condition

  • Might vary widely and may affect further body systems. The absence of a rash does not rule out the presence of other early signs of hypersensitivity such as fever or lymphadenopathy.
  • There has been one fatal instance of DRESS documented in the postmarketing environment, and it happened only three weeks after therapy with Armodafinil began. Furthermore, there has been a correlation between the beginning of Armodafinil use and the occurrence of multi-organ hypersensitivity events, including at least one death in post-marketing experience. Few cases have been reported, however, multi-organ hypersensitivity responses may be quite serious. Buy

Constant Tiredness

  • Armodafinil users who suffer from excessive drowsiness should be warned that their alertness may not return to normal even after taking the drug. Patients with extreme drowsiness, including those using Armodafinil, should have their level of sleepiness regularly reevaluated, and if necessary, they should be encouraged to refrain from driving or other potentially harmful activities. Additionally, prescribers should be mindful that patients may deny experiencing tiredness or drowsiness until prompted to do so.

Conditions of the Mind

  • Anxiety, agitation, nervousness, and irritability were more common in patients on Armodafinil than in patients on placebo in randomised controlled trials for narcolepsy, obstructive sleep apnea, and shift work disorder. Armodafinil patients were more likely than placebo patients to drop out of therapy due to depression (0.6% vs. 0.2%). Clinical research revealed several patients had suicidal thoughts.Buy Armodafinil smart pill online at a cheap price at Smartfinil. It may be necessary to stop taking Armodafinil if mental symptoms appear in tandem with its use.

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